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Updated: May 21, 2025

Isolation of Epithelial Cells from Human Dental Follicle
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综合的多omics分析描述了人类牙上皮在牙发育过程中的关键作用

Ran Zhang1, Zongshan Shen2, Zhenni Zhao3

  • 1Beijing Laboratory of Oral Health, School of Basic Medical Sciences, Capital Medical University, Beijing, China; Department of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.

Cell reports
|March 22, 2025
PubMed
概括

这项研究使用先进的多组学绘制了早期人类牙发育的地图,揭示了新的上皮细胞类型和对牙形成至关重要的信号. 这些发现提供了有关牙发育和再生的见解.

关键词:
CP: 发育生物学牙上皮质 牙上皮质人类胎儿牙发育的发展一些秘密一些秘密.一个单细胞RNA测序.空间转录学 空间转录学

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Teeth01:15

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
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