在胎儿的膀和运动功能的超声波评估与开放的分脊椎:队列研究研究
L Van der Veeken1,2,3, L De Catte1, A Hindryckx1
1Clinical Department of Obstetrics and Gynaecology, University Hospitals Leuven, Leuven, Belgium.
概括
产前超声检查揭示了开放脊柱裂 (OSB) 的胎儿的膀功能和运动技能异常,预测了产后的结果. Talipes 的存在会使运动功能恶化,无论损伤程度如何.
科学领域:
- 产前诊断和胎儿医学
- 儿科神经病学和泌尿病学
- 医学成像和超声波技术
背景情况:
- 开放性脊柱裂变 (OSB) 是一种先天性疾病,经常导致下肢和膀功能障碍.
- 胎儿发育的产前评估对于理解OSB的长期影响至关重要.
- 调查功能障碍的早期标志物可以改善产后管理和结果.
研究的目的:
- 通过超声波记录胎儿膀和下肢运动功能,在一个患有OSB的胎儿队列中.
- 调查产前发现与产后功能障碍之间的关联.
- 评估塔利普斯对产前和产后运动功能的影响.
主要方法:
- 一项前性横截面队列研究包括69名患有孤立OSB的胎儿,通过3D超声波进行评估.
- 胎儿膀体积和充空动力学被测量并与对照组进行比较.
- 产前运动功能通过关节运动进行评估;产后功能在1年后使用问卷和囊泡镜进行评估.
主要成果:
- 与对照组相比,OSB胎儿的膀体积较小,尿液流量减少,随着妊娠年龄的增加,差异越来越大.
- 产前运动功能是产后运动功能的更强的预测因素,而不是损伤水平,特别是在手术治疗的胎儿中.
- 与没有塔利佩的胎儿相比,塔利佩与明显更差的产后运动功能有关.
结论:
- 胎儿膀体积和OSB中的尿流异常存在于妊娠早期,独立于病变水平,并且可以预测产后尿液反流.
- 产前运动功能评估比解剖病变水平更可靠地预测产后运动功能障碍.
- 塔利普斯的存在会对OSB患者的产后运动功能产生负面影响.
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