肉症是局部 extremities/trunk wall 软组织肉瘤的一个负面预后因素
Tiziana Robba1, Vito Chianca2, Martina Rabino3
1Radiologia, Ospedale CTO, AOU Città della Salute e della Scienza di Torino, Italy.
概括
皮症对生存有负面影响,并增加了四肢和干部壁软组织肉瘤 (ESTS) 患者的并发症. 这项研究强调了sarcopenia作为ESTS结果的关键预后因素.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 老年病的医生 老年病的医生
背景情况:
- 骨肌肉质量和功能的损失,即萨尔科佩尼亚,是癌症患者的新兴预后决定因素.
- 有限的数据存在于sarcopenia对四肢和干部壁软组织肉瘤 (ESTS) 的影响.
研究的目的:
- 评估萨科佩尼亚对ESTS患者的预后和结果的影响.
主要方法:
- 使用SliceOMatic软件从CT扫描中测量骨肌面积 (SMA),皮下脂肪面积 (SFA) 和内脏脂肪面积 (VFA).
- 计算的骨质量指数 (SMI) 和肌肉密度 (MD).
- 使用卡普兰-梅尔分析将这些参数与术后并发症和生存率相关联.
主要成果:
- 总体存活率显著降低了sarcopenic患者 (低SMI和低MD).
- 麻症患者表现出增加术后并发症的趋势 (30.5%与17.0%相比).
- 在老年患者中或基于其他预后因素的基础上,肉症的患病率并没有显著增加.
结论:
- 在ESTS患者中,肉症似乎是一个负面的预后因素.
- 进一步调查萨科佩尼亚在ESTS中的作用是有必要的.
- 萨科佩尼亚评估可能有助于ESTS患者的风险分层和治疗规划.
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