重新审查儿童上肢手术中抗生素预防的必要性
Nathan Khabyeh-Hasbani1, Yufan Yan2, Yossef Rubinov1
1Division of Hand Surgery, Department of Orthopaedic Surgery, Montefiore Einstein, USA.
Injury
|March 22, 2025
概括
在儿科上肢手术中,可能不需要常规抗生素预防. 这项研究发现,接受抗生素和不接受抗生素的儿童之间的手术部位感染率没有显著差异.
科学领域:
- 整形外科手术 整形外科手术
- 儿科手术 儿科手术
- 传染性疾病 传染性疾病
背景情况:
- 最近的文献质疑成年人干净手术中的常规抗生素预防.
- 关于儿童上肢和手术中抗生素预防的必要性缺乏共识.
研究的目的:
- 调查抗生素预防是否影响儿科上肢手术中的术后手术部位感染 (SSI) 率.
主要方法:
- 对经过清洁UE手术的儿科患者的回顾性审查 (2021年11月至2023年11月).
- 主要结局:SSI诊断在14天和30天.
- 统计分析包括奇平方,费舍尔精确和威尔科克森等级和值测试 (p < 0.05显著).
主要成果:
- 分析了396名儿科患者;217人接受了手术前的抗生素,179人没有.
- 抗生素组SSI的发病率为0.9%,无抗生素组为1.1%.
- 在SSI率上没有统计学上显著的差异 (p = 0.846).
结论:
- 这些发现挑战了儿科UE手术中术前抗生素的必要性.
- 没有观察到SSI率的统计差异,无论抗生素预防.
- 建议对更多人群进行进一步的随机对照试验,以确认这些发现.
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