在对贫困和神经发育的研究中考虑种族和种族时的考虑因素
Clementine Semanaz1, Akhgar Ghassabian2, Scott Delaney1
1Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
概括
贫困对儿童神经发育的影响在种族和种族群体之间不同. 种族和种族是关键因素,用其他健康的社会决定因素取代它们可能会在研究中引入偏见.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 公共卫生 公共卫生
背景情况:
- 贫困和系统性种族主义不成比例地影响边缘化的种族和民族群体,导致儿童的不良精神病结果.
- 人种和种族经常被用作神经发育研究中的混因素,但这种做法仍在争论中.
- 建议替代健康的社会决定因素 (SDoH) 变量取代种族和种族作为系统性不利因素的衡量标准.
研究的目的:
- 调查种族和种族在贫困和儿童神经发育之间的关系中作为混因素与基本变量的作用.
- 为了比较种族和种族调整与替代SDoH变量对贫困结果关联的影响.
- 探索贫困和种族/种族之间的相互作用,影响精神症状,大脑结构和认知.
主要方法:
- 在青少年大脑认知发展 (ABCD) 研究中分析了7836名儿童的数据.
- 混合回归模型用于评估家庭贫困与精神病,神经成像 (MRI) 和认知结果之间的关联.
- 模型配备有或没有种族/种族调整,种族/种族贫困互动条款,以及其他SDoH变量.
主要成果:
- 贫困和精神病/认知结果之间的关系在种族和族群之间有显著差异 (p < .05相互作用).
- 对种族和种族进行调整,改变了贫困对MRI衍生皮质测量的估计影响.
- 其他SDoH变量并没有充分考虑这些关联中种族和种族的影响.
结论:
- 贫困和种族/种族相互作用,影响儿童的神经发育,表明贫困的影响在不同群体中不均.
- 这些发现支持在神经发育研究中将种族和种族视为关键因素的重要性,而不仅仅是混因素.
- 用其他SDoH指标取代种族/种族可能会导致偏见的结果;研究应该分层或包括相互作用术语.
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