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Updated: May 21, 2025

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
07:34

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice

Published on: December 16, 2021

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在炎症性肠道疾病中,公共克隆T细胞种群的抗原驱动扩张

Mitchell Pesesky1, Ramit Bharanikumar1, Lionel Le Bourhis2

  • 1Adaptive Biotechnologies, Seattle , Washington,  USA.

Journal of Crohn's & colitis
|March 22, 2025
PubMed
概括

这项研究确定了炎症性肠病 (IBD) 患者血液中的特定T细胞受体 (TCR) 信号,区分克罗恩病 (CD) 和性结肠炎 (UC). 这些发现揭示了IBD和潜在的诊断生物标志物的独特免疫反应.

关键词:
克罗恩氏病是什么 克罗恩氏病是什么T细胞受体受体的 T 细胞受体.人类白细胞抗原.性结肠炎是一种

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