ALK2R206H突变受体和自信号之间的相互作用调节受体稳定性及其体功能

Laura Coculo1,2, Marius Wits3, Irene Mariani1,2

  • 1Institute of Molecular Biology and Pathology, National Research Council (CNR), Rome, Italy.

Cell death discovery
|March 23, 2025
PubMed
概括

纤维发育不良性骨渐进性 (FOP) 涉及突变的ALK2受体信号传递. 这项研究表明,受损的自流稳定了突变ALK2,推动了疾病的进展,并建议作为治疗策略重新激活自.

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