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Updated: May 21, 2025

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE
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Published on: July 29, 2014

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复合到双链RNA的LL37诱导RIG-I类受体信号和Gasdermin E激活,促进IL-36γ从角质细胞释放

Jennifer Keller1, Judit Danis1,2,3, Isabella Krehl1

  • 1Department of Dermatology, University Hospital Zürich (USZ), University of Zürich (UZH), Raemistrasse 100, 8091, Zürich, Switzerland.

Cell death & disease
|March 23, 2025
PubMed
概括

角质细胞通过涉及双链RNA (dsRNA) 和LL37的不同途径释放Interleukin-36 gamma (IL-36γ). 这些机制,包括Gasdermin E孔隙形成或炎症酶激活,影响IL-36γ处理和牛皮病原体.

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