探索 GCOS-16 对扩展应用的潜在实用性
Yvette Kuo1, Kennedy Borle2, Jehannine Austin3
1Department of Medical Genetics, Genetic Counseling Program, University of British Columbia, Vancouver, BC, Canada.
European journal of human genetics : EJHG
|March 23, 2025
概括
遗传咨询结果尺度-16 (GCOS-16) 有效地衡量了遗传咨询后的患者赋权,显示了显著的改善. 这种尺度可以帮助确定从遗传咨询服务中受益最多的患者.
科学领域:
- 心理测量 心理测量 心理测量
- 基因咨询 基因咨询
- 患者赋权是患者赋权的一种方式.
背景情况:
- 遗传咨询结果尺度-24 (GCOS-24) 可靠地衡量了赋权,但也有局限性.
- 拉什测量理论被用来开发GCOS-16,一个更短的尺度,简化了响应格式.
- GCOS-16表现出更好的性能和在遗传服务中更广泛应用的潜力.
研究的目的:
- 使用统计方法确定GCOS-16的临床重要差异最小值 (MCID).
- 评估GCOS-16或其子域是否可以识别那些从遗传咨询 (GC) 中受益最多的患者.
- 评估GCOS-16对变化的敏感性和对患者分组和对干预措施进行比较的潜力.
主要方法:
- 在精神病学GC诊所进行的307次GCOS-24评估的数据被转化为GCOS-16评分 (16项,3点利克特等级).
- 使用统计分析计算了GCOS-16.16的MCID.
- 基因咨询前和后的得分进行了比较,以评估赋权的变化.
主要成果:
- 从GC前期到GC后期,GCOS-16得分显著增加 (p < 0.001,d = 0.935).
- 对于GCOS-16来说,MCID被确定为2.5个点的增加.
- 与远程医疗或电话服务相比,接受面对面GC的患者更有可能实现MCID (p < 0.001).
结论:
- GCOS-16是基因咨询后赋权变化的敏感和可靠的衡量标准,没有天花板效应.
- 可以利用GCOS-16进行患者分组,并比较GC与其他干预措施的有效性.
- 面对面的遗传咨询似乎更有效地实现了临床上重要的患者赋权改进.
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