怀孕期间使用大麻与2岁儿童认知,运动和语言发育之间的纵向关联
Justine Pleau1,2,3,4, Noémie Tanguay1,2, Yohann Courtemanche2
1École de psychologie de l'Université Laval, Quebec City, QC, Canada.
Maternal and child health journal
|March 23, 2025
概括
产前大麻使用与儿童发育迟缓无关. 然而,观察到大麻使用与女孩语言发展之间存在积极的关联,这表明性别特异性影响.
科学领域:
- 产科和妇科 产科和妇科
- 儿科发展 儿科发展
- 公共卫生 公共卫生
背景情况:
- 怀孕期间使用大麻是一个越来越令人担忧的问题.
- 了解它对儿童发育的影响至关重要.
研究的目的:
- 描述产前大麻使用模式.
- 为了确定相关的母性因素.
- 检查产前大麻暴露对2岁儿童发育的影响.
- 调查这些影响的性别特异性差异.
主要方法:
- 对1489个母婴双进行前性队列研究.
- 大麻使用量通过跨季度的采访进行评估.
- 在2岁时使用贝利婴幼儿发育量表 (BSID-III) 和麦克阿瑟-贝茨沟通发育库存评估儿童发育.
- 统计分析包括多重线性回归和性别差异分析.
主要成果:
- 2.6%的妇女报告产前使用大麻,通常在头三个月后停止使用.
- 大麻使用与较低的社会经济地位,同时使用酒精/烟草和孕产妇痛苦有关.
- 在产前使用大麻与认知,精细运动或粗运动发育之间没有发现显著的关联.
- 大麻使用与语言发育之间的积极关联仅在女孩身上被观察到.
结论:
- 在这个队列中,产前大麻暴露对整体儿童发育没有显著的负面影响.
- 与女孩语言发育的潜在积极关联需要进一步研究.
- 未来的研究应该利用生物标志物准确记录产前大麻暴露.
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