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用跨直肠内孔MRI活检检测前列腺癌:前列腺体积和病变特征的影响
Alexander Schaudinn1,2, Harald Busse3, Constantin Ehrengut3,4
1Department of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Germany. alexander.schaudinn@medizin.uni-leipzig.de.
通过直肠内MRI导向的活检显示出一致的癌症检测率,无论前列腺体积或病变特征如何. 这表明即使在复杂的活检场景中,诊断性能也可靠.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 跨直肠内孔MRI导向活检越来越多地用于前列腺癌诊断.
- 前列腺和病变特征对活检结果的影响仍然是研究的主题.
研究的目的:
- 系统地分析前列腺体积和病变特征如何影响穿直肠内MRI导向前列腺活检的诊断结果.
- 为了确定具有挑战性的活检设置是否会损害诊断性能.
主要方法:
- 追溯分析184名接受了穿直肠内孔MRI导向活检的患者.
- 评估前列腺体积,病变大小,位置和深度与临床显著前列腺癌 (cs-PCa) 和任何前列腺癌 (any-PCa) 的癌症检测率 (CDR) 相比.
- 使用分类和连续变量进行统计比较.
主要成果:
- 在201个活检病变中,cs-PCa的总检测率为26%,任何PCa的总检测率为68%.
- 亚组分析显示,仅基于病变大小的cs-PCa CDR有显著差异 (p < 0.001).
- 多变量分析确定PI-RADS得分和PSA是c-PCa风险的重要预测因素.
结论:
- 前列腺体积,病变大小和病变位置并没有显著影响穿直肠内MRI导向活检中的癌症检测率.
- 这些发现表明,在具有挑战性的活检情况下,诊断性能不会受到损害.
- 这项研究强调了在各种患者和病变特征中,穿孔MRI导向活检的稳定性.
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