乳腺癌患者放射治疗的特定类型焦虑:一项纵向研究
Shi-Jia Wang1, Xin Feng1, Wei Zhang1
1State Key Laboratory of Molecular Oncology, Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Breast cancer (Tokyo, Japan)
|March 23, 2025
概括
这项研究验证了乳腺癌患者的中国放射治疗分类焦虑量表 (RCAS),发现对副作用的焦虑和治疗疗效在放射治疗期间保持稳定.
科学领域:
- 在瘤学瘤学.
- 心理学 心理学 心理学
- 医学社会学 医学社会学
背景情况:
- 放射治疗 (RT) 可以诱导癌症患者显著的焦虑.
- 放射治疗分类焦虑量表 (RCAS) 衡量了与放射治疗相关的特定焦虑.
- 在中国乳腺癌 (BC) 患者中验证RCAS对于文化相关的评估至关重要.
研究的目的:
- 翻译并验证RCAS为BC患者的中文.
- 评估中国RCAS的可靠性和有效性.
- 在整个RT过程中评估特定RT相关焦虑类型和水平的变化.
主要方法:
- 对504名接受RT的中国BC患者进行前性纵向研究.
- 在多个时间点处方中国RCAS,PHQ-9 (抑郁症) 和GAD-7 (焦虑症).
- 使用通用估计方程和多变量通用线性模型进行分析.
主要成果:
- 中国的RCAS显示出高的内部一致性 (克朗巴赫的α=0.89-0.92) 和有效性.
- 对RT环境的担忧减少,而对治疗疗效的担忧保持稳定.
- 较高的基线情绪困扰预测了更大的RT相关焦虑.
结论:
- 中国的RCAS是评估中国BC患者RT相关焦虑的可靠工具.
- 临床医生应关注患者对副作用和治疗疗效的担忧.
- 患有基线情绪困扰的患者需要特别注意与RT相关的焦虑.
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