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Updated: May 21, 2025

Author Spotlight: Evaluating Biophysical Assays for Characterizing PROTACS Ternary Complexes
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Published on: January 12, 2024

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质谱学的应用,以促进 PROTACs 的发展

Yuechen Hao1, Baoshuang Zhang1, Ruibing Chen1

  • 1School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin 300072, China.

Journal of pharmaceutical and biomedical analysis
|March 23, 2025
PubMed
概括

化向化体 (PROTACs) 通过降解向蛋白来提供新的疾病治疗方法. 质谱 (MS) 对于 PROTAC 开发至关重要,有助于目标识别,疗效验证和机制阐明.

关键词:
质谱测量质量谱测量这就是 PROTACs.蛋白质组学是指蛋白质组学.有针对性的蛋白质降解降解.

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