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Updated: Jun 22, 2026

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综合测绘揭示了原发性转移性乳腺癌中的高风险基因型

Tobias Berg1, Lise Ahlborn2, Maj-Britt Jensen3

  • 1Danish Breast Cancer Group, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Neoplasia (New York, N.Y.)
|March 23, 2025
PubMed
概括

在原发性转移性乳腺癌 (pMBC) 中的基因组分析揭示了可向突变. 早期遗传分析可以指导个性化治疗策略,以改善患者的治疗结果.

关键词:
乳腺癌 乳腺癌 乳腺癌基因组学就是基因组学.转移性 转移性

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...