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Updated: May 20, 2025

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布里加替尼激活炎症酶:与免疫相关的不良事件有关

Takumi Noda1, Saori Tanaka1, Yuto Maruta1

  • 1Department of Pharmacotherapeutics and Toxicology, Faculty of Pharmacy, Osaka Medical and Pharmaceutical University, Osaka 569-1094, Japan.

Toxicology and applied pharmacology
|March 23, 2025
PubMed
概括

布里加替尼 (Brigatinib) 是一种ALK抑制剂,直接激活炎症体,引起免疫反应. 这种药物诱导的肝细胞炎酶激活可能解释了布里加替尼的存在.

关键词:
布里加替尼布的使用情况与损伤相关的分子模式.炎症性酶体 (inflammasomes) 是一种炎症性酶体.反应性代谢物反应性代谢物

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