长期COVID的运动干预措施的有效性和耐受性:随机对照试验的系统审查
Cillian P McDowell1, Barrie Tyner2, Shibu Shrestha2
1Health Information and Quality Authority, Dublin, Ireland cmcdowell@hiqa.ie.
BMJ open
|March 23, 2025
概括
运动干预措施对疲劳和呼吸障碍等长期COVID症状显示出短期益处,并且通常耐受良好. 然而,由于研究规模和随访时间有限,需要进行更多的研究.
科学领域:
- 康复医学 康复医学 康复医学
- 传染性疾病 传染性疾病
- 运动生理学 运动生理学
背景情况:
- 长期COVID是一种复杂的后病毒综合征,呈现出多样化和持久的症状,影响生活质量.
- 正在探索运动干预作为一种潜在的治疗策略,用于管理长期的COVID病情.
- 了解运动的有效性和安全性对于制定基于证据的康复方案至关重要.
研究的目的:
- 系统地审查运动干预措施在改善长期COVID症状方面的有效性.
- 评估长期COVID患者的运动计划的耐受性和安全性.
- 综合当前关于运动对核心长期COVID结果的影响的证据.
主要方法:
- 随机对照试验的系统审查.
- 在Medline,Embase和CENTRAL数据库中进行的搜索截至2023年2月28日.
- 纳入标准侧重于患有长期COVID的参与者,随机运动干预和定量结果测量;排除标准指的是非COVID相关的疾病和以呼吸系统为重点的培训.
主要成果:
- 包括8项研究,平均涉及56名参与者 (范围为39-119人),随访期平均为8.5周.
- 运动干预措施在呼吸障碍,疲劳,身体功能和生活质量方面显示出短期改善.
- 副作用是罕见和轻微的;252名参与者中只有1人因耐受性问题而停止服用.
结论:
- 目前的证据表明,运动干预措施可能会带来好处,并且对于一些长期COVID患者来说通常是可以容忍的.
- 现有的证据基础受到少数研究,小样本大小和短期随访持续时间的限制.
- 需要进一步的高质量研究来证实这些发现,并建立长期COVID的最佳运动方案.
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