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Updated: May 20, 2025

Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen
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Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen

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乌斯图索拉特E和11α-氧-乌斯图索拉特E通过调节PI3K/AKT/mTOR和p-53通路,诱导癌细胞系的亡

Mewlude Rehmutulla1, Sitian Zhang1, Jie Yin1

  • 1Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Chinese journal of natural medicines
|March 23, 2025
PubMed
概括

新的天然化合物乌斯图索拉特E (UE) 和11α--乌斯图索拉特E (HUE) 显示出强大的抗癌活性. 这些化合物有效地抑制癌细胞生长并诱导细胞亡,为新药开发提供了潜力.

关键词:
11α-氧 - 乌斯托索拉特E癌症 癌症 癌症 癌症在PI3K/AKT/mTOR路径中.乌斯图索拉特 (Ustusolate) 是一个独立的生物.p-53 路径 路径

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