与早产婴儿的鼻CPAP相比,使用高流量鼻进行肺空气的变化
Anup Katheria1, Felix Ines2, Judith Hough3
1Neonatal Research Institute, Sharp Mary Birch Hospital for Women & Newborns, San Diego, CA, USA. anup.katheria@sharp.com.
高流量鼻腔管 (HFNC) 在降低早产婴儿的脱鼻症方面与鼻持续气道压力 (nCPAP) 一样有效. 经历HFNC失败的婴儿表现出增加的肺气化问题.
科学领域:
- 新生儿的呼吸系统支持.
- 在早产婴儿的肺生理学
背景情况:
- 过早出生的婴儿通常需要由于肺部发育不良而需要呼吸支持.
- 鼻连续气道压力 (nCPAP) 和高流量鼻管 (HFNC) 是呼吸辅助的常见方法.
研究的目的:
- 为了比较HFNC与nCPAP在治疗早产婴儿的乳腺增生症方面的疗效.
- 在接受nCPAP和HFNC的婴儿中使用电阻断层扫描 (EIT) 评估肺空气.
主要方法:
- 一个交叉研究设计,涉及婴儿不到29周的妊娠年龄.
- 婴儿接受了6小时的HFNC试验,每分钟8升,交替与nCPAP.
- 电阻断层扫描 (EIT) 用于量化肺空气,特别是依赖静音空间 (DSS).
主要成果:
- 在整个研究期间,在维持肺气化方面,HFNC被发现与nCPAP无差.
- 与那些忍受不了HFNC的婴儿相比,HFNC失败的婴儿表现出明显更高的依赖静音空间 (DSS) 百分比.
- 这表明,肺气化减少可能与HFNC失效有关.
结论:
- 8L/分钟的HFNC是nCPAP的可行的替代品,用于早产婴儿 (<29周GA) 的呼吸支持.
- 在HFNC失败的婴儿中增加的DSS表明肺空气的潜在挑战,需要进一步调查.
- 欧洲呼吸系统是评估肺空气和指导新生儿呼吸辅助策略的宝贵工具.
更多相关视频
07:51Evaluation of Capnography Sampling Line Compatibility and Accuracy when Used with a Portable Capnography Monitor
Published on: September 29, 2020
04:56Laryngeal Mask Airway LMA Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway SGA
Published on: July 14, 2023
相关概念视频
Administering Oxygen by Nasal Cannula
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
Oxygen Delivering System I: Nasal Cannula and Face Mask
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Factors Affecting Pulmonary Ventilation
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
