慢波睡眠和快速眼动睡眠都会促进情感记忆的巩固和巩固
Cagri Yuksel1,2,3, Dan Denis4,5,6, James Coleman4
1Center for Sleep and Cognition, Beth Israel Deaconess Medical Center, Boston, MA, USA. ayuksel@mgb.org.
Communications biology
|March 24, 2025
概括
在慢波睡眠 (SWS) 期间对目标记忆的重新激活有利于情感记忆的巩固. 令人惊的是,在快速眼动睡眠 (REM) 期间重新激活记忆会损害回忆,这表明REM可能有助于忘记.
科学领域:
- 神经科学是一个神经科学.
- 睡眠科学 睡眠科学
- 认知心理学 认知心理学
背景情况:
- 睡眠对于记忆巩固至关重要,但睡眠阶段的不同作用,特别是慢波睡眠 (SWS) 和快速眼动睡眠 (REM),在处理情感记忆方面尚未完全理解.
- 虽然REM睡眠传统上与情感记忆处理有关,但新出现的证据表明SWS在加强这些记忆方面发挥了作用.
研究的目的:
- 通过针对性记忆再激活 (TMR) 来研究SWS和REM睡眠在巩固情感声明记忆中的特定作用.
- 为了确定情感记忆的巩固是否主要由SWS或REM睡眠促进.
主要方法:
- 在白天小睡期间利用有针对性的记忆重新激活 (TMR),在SWS和REM睡眠期间选择性地提示情绪和中性声明记忆.
- 监测睡眠架构和脑电图 (EEG) 活动,包括delta/theta功率和睡眠.
- 评估TMR后的记忆性能,以评估整合效应.
主要成果:
- 与最初的假设相反,REM睡眠期间的TMR导致对情绪刺激的记忆回忆受损.
- 在SWS期间的TMR益处与REM和SWS周期的持续时间正相关.
- 与中性记忆相比,情感记忆的巩固得到了增强,情感价值调节了EEG活动,特别是三角形/三角形功率和睡眠.
结论:
- 在巩固情感记忆方面,SWS和REM睡眠似乎具有互补的,而不是重叠的作用.
- 快速眼神睡眠可能参与遗忘或下调情感记忆,而快速眼神睡眠则有助于加强情感记忆.
- 研究结果强调了睡眠,情绪价值和睡眠期间的记忆处理之间的复杂关系.
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