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在年轻男性中WVTT (摘要) 的安全性和有效性:初步数据
Antonio Minore1, Loris Cacciatore2, Giovanni Ferrari3,4
1Department of Urology, Fondazione Policlinico Campus Bio Medico di Roma, Via Alvaro Del Portillo 200, 00128, Rome, Italy. antonio.minore@gmail.com.
International urology and nephrology
|March 24, 2025
概括
水蒸气热疗法 (WVTT) 为年轻男性提供安全有效的微创治疗,这些年轻男性因良性前列腺增生 (LUTS/BPH) 而出现下尿路症状. 在50岁以下的患者中,Rezūm治疗显示出显著的功能改善和保持射精功能.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 最少侵入性的手术
- 医疗器械 医疗器械
背景情况:
- 良性前列腺增生 (BPH) 和与之相关的下泌尿道症状 (LUTS) 显著影响生活质量.
- 水蒸气热疗法 (WVTT) 代表了对LUTS/BPH的一种新的微创手术治疗 (MIST) 选择.
- 关于WVTT在年轻患者群体 (<50岁) 的功能结果的数据有限.
研究的目的:
- 为了评估50岁以下患者的功能结局,用Rezūm (一种特定的WVTT装置) 治疗BPH.
- 评估治疗后尿液流量,排泄症状和性功能的改善.
- 为了确定WVTT在这个人口群体中的安全性和可行性.
主要方法:
- 展望性研究涉及10名50岁以下的患者,在5个机构接受了Rezūm治疗.
- 数据收集包括尿液流量测量,前列腺特异性抗原 (PSA),超声波 (前列腺体积,空白后残留体积 - PVR),国际前列腺症状评分 (IPSS),国际勃起功能指数 (IIEF-5) 和射精功能障碍评估.
- 测量是在基线和治疗后3,6个月和12个月进行的.
主要成果:
- 所有患者在IPSS得分,最大流速 (Qmax) 和PVR3个月后显著改善,持续至12个月.
- 所有参与者均保持或改善了射精功能.
- 该手术是安全的,中位数的手术时间为9分钟,仅有一例尿管切除后的尿.
结论:
- 使用Rezūm的WVTT是年轻男性 (<50岁) 经历LUTS/BPH的可行和安全的最小侵入性治疗选择.
- 治疗产生最佳的早期功能结果,包括显著的症状缓解和性功能保存.
- 这项研究支持WVTT作为这个特定患者群体的有价值的治疗选择.
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