累积的压力暴露和儿童后期的认知功能:炎症的作用
Izabella Polgar-Wiseman1, Marta Francesconi1, Eirini Flouri1
1Department of Psychology and Human Development, Institute of Education, University College London, London, UK.
The British journal of developmental psychology
|March 24, 2025
概括
儿童时期的压力和炎症与执行功能和社会沟通问题有关. 虽然炎症并没有介导压力的影响,但它与执行功能障碍有关,而压力与社会沟通困难有关.
科学领域:
- 儿童心理学 儿童心理学
- 神经科学是一个神经科学.
- 免疫学 免疫学 免疫学
背景情况:
- 早期的生活压力会影响儿童的发展.
- 炎症与各种健康状况有关.
- 执行功能和社会沟通对于发展至关重要.
研究的目的:
- 研究儿童早期生活压力因素,炎症和晚期执行功能和社会沟通之间的关系.
- 探索炎症是否介导压力生活事件对认知和社会结果的影响.
主要方法:
- 利用了4457名参与者在阿文长度研究的父母和儿童 (ALSPAC) 的数据.
- 研究了从婴儿期到8.5岁的压力生活事件.
- 在10-11岁时评估执行功能 (工作记忆,响应抑制,选择性注意力,注意力控制) 和社会沟通 (沟通问题,社会认知).
- 在9岁时测量了炎症 (互白素6和C反应蛋白).
主要成果:
- 没有证据表明炎症介导压力生活事件对执行功能或社会沟通的影响.
- 在炎症和执行功能障碍之间发现了一个小但强大的关联.
- 紧张的生活事件与社交沟通困难有关.
结论:
- 炎症与儿童的执行功能缺陷有关.
- 压力较大的生活事件与社会沟通挑战有关.
- 减少炎症可能会改善儿童的执行功能.
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