种族和事件痴呆症在老年黑人和老年白人男性中
Bosola Jerry-Asooto1,2, Boeun Kim3, Alison Huang4
1Program for Research on Men's Health, Johns Hopkins Center for Health Disparities Solutions, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Journal of aging and health
|March 24, 2025
概括
与白人男性相比,年长的非西班牙裔黑人男性患痴呆症的风险更高. 独特的生活压力因素,遗传模式或营养可能导致这种差异.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 神经科学是一个神经科学.
背景情况:
- 痴呆风险受到各种因素的影响,包括种族和种族.
- 了解痴呆症发病率的种族差异对于有针对性的公共卫生干预至关重要.
- 国家健康和衰老趋势研究 (NHATS) 提供了美国人口健康和衰老的纵向数据.
研究的目的:
- 调查年龄较大的非西班牙裔黑人 (NHB) 男人和非西班牙裔白人 (NHW) 男人之间痴呆发病率的种族差异.
- 通过使用NHATS数据,分析11年 (2011-2022) 的痴呆风险.
- 识别可能导致痴呆症观察到的种族差异的潜在因素.
主要方法:
- 利用来自NHATS的2395名社区住户NHB和NHW男性的数据,在基线时所有人都没有痴呆症.
- 采用NHATS为每个参与者访问开发的经过验证的痴呆症评估算法.
- 应用了考克斯的比例危险模型,根据人口,地理和健康相关特征进行调整.
主要成果:
- 较年长的NHB男性与较年长的NHW男性相比,发生痴呆症的风险显著增加 (危险比:1.63,95%CI: [1.22-2.17]).
- 对共同变量的统计调整并没有消除痴呆风险中观察到的种族差异.
- 这些发现强调了两种种族群体之间痴呆发病率的显著差异.
结论:
- 年长的NHB男性比NHW男性患病痴呆症的风险更高.
- 潜在的促成因素可能包括独特的压力因素,遗传倾向或NHB男性经历的营养模式.
- 需要进一步的研究来阐明这些种族差异的痴呆风险背后的具体机制.
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