餐后高糖血症查和怀孕结果 - - 从COVID-19中吸取教训
Beenu Bastian1,2, Lisa Gaye Smithers3, Ansar Kunjunju4
1School of Medical Indigenous and Health Sciences, University of Wollongong, Wollongong, New South Wales, Australia.
概括
澳大利亚COVID-19孕期糖尿病查减少了口服葡萄糖耐受性测试的需要. 孕产妇和新生儿的结局在低禁食葡萄糖和正常葡萄糖耐受度的妇女之间是可比的.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 孕期糖尿病 (GDM) 的诊断和治疗在COVID-19期间有所不同.
- 澳大利亚的指导方针将禁食葡萄糖<4.7 mmol/L的妇女排除在GDM诊断之外.
- 这项研究检查了女性的结果,在改变查协议下,她们的禁食葡萄糖降低.
研究的目的:
- 描述孕妇的孕产妇和新生儿结局,其禁食血糖<4.7 mmol/L.
- 根据COVID-19之前和期间的不同GDM诊断和治疗途径来比较结果.
- 评估修改的GDM查协议的影响.
主要方法:
- 基于人口的数据链接研究,对3891名女性的禁食血糖<4.7 mmol/L (怀孕24-32周).
- 分类为三个组:食后高血糖症 (PPGDM),正常葡萄糖耐受性 (NGT) 和低禁食血糖 (LFBG),没有测试食后高血糖症.
- 使用通用线性模型比较围产期结局.
主要成果:
- 在PPGDM和NGT组之间,对于孕期大婴儿的风险没有显著差异.
- 与NGT组相比,PPGDM组的平均出生体重较低.
- 在LFBG组的孕产妇和新生儿结局在很大程度上与NGT组相似.
结论:
- 澳大利亚的COVID-19 GDM查协议,强调初始禁食葡萄糖,减少了67%的口服葡萄糖耐受性测试的需要.
- 妇女的饮食后高糖血症的诊断和治疗 妇女的饮食后高糖血症的诊断和治疗 妇女的饮食后高糖血症的诊断和治疗 需要考虑利益与成本.
- 修改后的查协议会影响GDM管理中的诊断途径和资源利用.
相关概念视频
01:22Diabetes Mellitus: Type 2 and Gestational
2.1K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.1K
01:20Pathophysiology of Diabetes
833
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
833
01:15Diabetes: Symptoms, Diagnosis, and Complications
494
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
494
01:19Overview of Carbohydrate Metabolism
619
Carbohydrate metabolism is a fundamental biochemical process that ensures a constant supply of energy to living cells. The most important carbohydrate is glucose, which can be broken down via glycolysis to enter into the Krebs cycle and eventually lead to the production of ATP through oxidative phosphorylation.
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
619
01:15Hypoglycemia and Glucagon
143
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
143
01:22Diabetes Mellitus: Overview and Type I Subtype
2.3K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.3K