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Updated: May 20, 2025

Real-Time Monitoring of Aurora kinase A Activation using Conformational FRET Biosensors in Live Cells
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"探索针对人类光激酶C的新型抗癌剂"

Deepali Gupta1, Prakash Kumar Shukla2, Subarnarekha Chowdhury1

  • 1Department of Biophysics, All India Institute of Medical Sciences, Delhi, India.

Journal of cellular biochemistry
|March 24, 2025
PubMed
概括

计算药物发现从数百万种化合物中确定了三种强大的光激酶C (AKC) 抑制剂. 这些新型候选药物在治疗与AKC水平升高相关的癌症方面表现有前途.

关键词:
光基因酶C 的作用癌症 癌症 癌症 癌症MMGBSA 的计算方法分子动力学模拟,分子动力学模拟

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