在多发性硬化症中,身体活动和认知功能之间是否存在值或剂量反应关联?
Brenda Jeng1, Gary R Cutter2, Robert W Motl1
1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL, USA.
概括
增加每天的步骤可能会改善多发性硬化症 (MS) 的认知功能. 在每天的步骤和认知测试得分之间发现了线性关系,这表明所有活动水平都有好处.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
- 临床神经学 临床神经学
背景情况:
- 认知障碍是多发性硬化症 (MS) 的一个重大挑战,影响日常生活和疾病管理.
- 身体活动,特别是每天的步数,已经显示出与多发性硬化症患者的认知健康的潜在联系.
研究的目的:
- 调查是否存在特定的每日步骤值,以避免MS患者的认知障碍.
- 确定MS患者的日常步骤和认知功能之间是否存在剂量反应关系.
主要方法:
- 358名患有多发性硬化症的参与者完成了认知测试 (SDMT,CVLT-II) 并佩戴加速度计7天,以测量每天的步骤.
- 收集了人口和临床数据,包括MS类型和残疾状况.
主要成果:
- 在SDMT或CVLT-II.II上没有特定的步骤/天值被确定为缺乏认知障碍.
- 回归分析显示,SDMT和CVLT-II的步骤/天和认知分数之间存在显著的线性关系.
结论:
- 在MS的日常步骤和认知功能之间存在线性关联,这表明更高的身体活动水平可能会提高认知表现.
- 对于患有多发性硬化症的人来说,无论他们目前的活动水平如何,鼓励他们每天增加步骤可能是对认知健康有益的策略.
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