心脏骤停后的睡眠障碍:患病率和与认知功能的关系
A B Glimmerveen1,2, J Bos1, E G J Zandbergen1
1Department of Neurology, Rijnstate Hospital, Arnhem, the Netherlands.
Resuscitation plus
|March 24, 2025
概括
睡眠障碍,特别是阻塞性睡眠呼吸暂停,在心脏骤停的幸存者中很常见,并且与认知障碍有关. 治疗睡眠呼吸暂停可能会改善这些患者的认知功能.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 心脏病学 心脏病学
背景情况:
- 在心脏骤停的幸存者中,长期认知障碍很普遍,通常归因于后毒性脑病变.
- 睡眠障碍经常被观察到脑损伤后,并可能加剧认知缺陷.
研究的目的:
- 为了确定心脏骤停幸存者的睡眠障碍的患病率.
- 在这个人群中调查睡眠障碍与认知功能之间的关联.
主要方法:
- 三十名心脏骤停幸存者经历了神经心理测试,问卷和多梦图,事件发生一年后.
- 客观睡眠参数 (睡眠呼吸暂停,腿部运动) 和主观报告与认知测试表现相关.
主要成果:
- 36%的人有中度至重度的阻塞性睡眠呼吸暂停 (OSA);43%的人在睡眠期间有中度至重度的周期性四肢运动.
- OSA与较差的执行功能和记忆相关. 睡眠周期较少与注意力减少有关.
- 主观睡眠和情绪评估与认知结果没有相关性.
结论:
- 中度至严重的睡眠障碍,特别是OSA,在心脏骤停幸存者中很常见.
- 阻塞性睡眠呼吸暂停与执行功能和记忆力受损显著相关.
- 诊断和治疗OSA可能是改善心脏骤停幸存者的认知能力的治疗目标.
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