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Updated: May 20, 2025

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
08:04

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Published on: October 23, 2018

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通过调节氨基酸介导的mTORC1激活,RAP1A可以抑制肝肥胖症

Heena Agarwal1,2, Yating Wang1,2,3, Brea Tinsley1,2

  • 1Department of Medicine, Columbia University Medical Center, New York, NY, USA.

JHEP reports : innovation in hepatology
|March 24, 2025
PubMed
概括

激活肝脏RAP1A通过减少肝脏脂肪和纤维化来对抗与代谢功能障碍相关的脂肪性肝病 (MASLD) 和脂肪性肝炎 (MASH). 这通过降低氨基酸吸收,抑制mTORC1和减少SREBP1裂变来实现.

关键词:
氨基酸是氨基酸的组成部分.马什 (MASH) 是一个非常重要的产品.马斯尔德 马斯尔德是什么意思在 RAP1A 中, RAP1A 是 RAP1A 的类型.在 mTORC1 的情况下,mTORC1 是

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