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Updated: May 20, 2025

Chemical Dimerization-Induced Protein Condensates on Telomeres
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富含p53的中等层聚类代表了一种新型的蛋白质凝聚物

David S Yang1, Alexander Tilson1, Michael B Sherman2

  • 1William A. Brookshire Department of Chemical and Biomolecular Engineering, University of Houston, 4226 M.L. King Blvd., Houston, Texas 77204-4004, USA.

Biophysics reviews
|March 24, 2025
PubMed
概括

突变的p53蛋白质形成独特的液体聚合物,促进粉样纤维的形成. 排序的蛋白质域是形成这些的关键,将突变与促进癌症的聚合联系起来.

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