在伪皮综合征中量化瞳孔扩张引起的眼内压力,角度和前段参数的变化,使用Scheimpflug成像
Maria N Boshra1, Hossam M Moharram1, Yehia M Khairat1
1Department of Ophthalmology, Minia University, Minya, Egypt.
Oman journal of ophthalmology
|March 24, 2025
概括
水剂在伪剥皮 (PEX) 患者中有效扩大瞳孔. 热胺提供了良好的平衡扩张和最小的眼内压力 (IOP) 增加,使其成为PEX患者更安全的选择.
科学领域:
- 眼科医生 眼科 眼科
- 药理学 药理学是指药理学的学科.
背景情况:
- 伪脱皮综合征 (PEX) 是二次光眼的常见原因之一.
- 眼剂对于眼科检查和手术至关重要.
- 了解流体对PEX前段参数的影响至关重要.
研究的目的:
- 为了比较烯,热皮卡米德和环酸盐在前段参数和眼内压力 (IOP) 上的疗效.
- 与健康对照组相比,在伪剥皮 (PEX) 患者中评估这些影响.
主要方法:
- 一项涉及25名PEX患者和16名对照者的横截面研究.
- 使用三种水性药物 (烯,热胺,环胺).
- 使用Scheimpflug成像测量IOP,视镜,前腔深度,体积,角度,瞳孔直径 (PD),中角膜厚度 (CCT) 和角膜体积的注射前后测量.
主要成果:
- 在PEX和对照组之间没有显著的基线差异,除了对照组中较厚的CCT.
- 在PEX患者中,Mydriatics增加了大多数前段参数,除了CCT和视镜测量.
- 烯诱导了最大的瞳孔扩张;热胺在PEX患者中显示了PD和IOP之间的负相关性.
结论:
- 这三种脑膜缩剂对PEX患者的瞳孔扩张都有效.
- 乙烯在临床和外科使用中非常有效.
- 由于平衡的扩张和最小的IOP升高,Tropicamide 1%对PEX患者具有有利的安全性.
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