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使用综合药物发现平台识别PPM1D的小分子抑制剂

Subrata Shaw1,2, Wei Jiang1,2, Jason Rush1,2

  • 1Broad Institute of MIT and Harvard University, Cambridge, MA, USA.

iScience
|March 24, 2025
PubMed
概括

研究人员确定了PPM1D的新型全抑制剂,这是DNA损伤反应 (DDR) 和p53的关键调节剂,为癌症治疗提供了新的治疗潜力.

关键词:
生物科学 生物科学药物 药物 药物 是一种药物.卫生科学 卫生科学医学 医学 医学 医学 医学自然科学 自然科学药理学 药理学是指药理学的学科.

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