同时进行激进囊切除术和尿切除术:一个案例系列
Gavin G Calpin1,2, Steven M Anderson1,2, Mark Broe1
1Department of Urology, Beaumont Hospital, Dublin 9, Ireland.
Surgery in practice and science
|March 24, 2025
概括
同时激进囊切除术和神经尿路切除术 (RCNU) 是治疗尿路癌 (UC) 和肌肉侵入性膀癌 (MIBC) 的复杂手术. 这项研究发现RCNU对全神经皮质癌和MIBC上道功能障碍有效.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 手术瘤学手术瘤学
背景情况:
- 同时激进囊切除术和神经尿路切除术 (RCNU) 是一种复杂的程序,适用于尿路细胞癌 (UC) 的特定病例.
- 指示包括多焦点高度UC或肌肉侵入性膀癌 (MIBC) 与脏受损.
研究的目的:
- 审查RCNU程序的指示,操作方法和结果.
- 评估RCNU在患有晚期UC和上路损伤的患者中的有效性.
主要方法:
- 在2015-2024年期间,对接受RCNU的患者进行了单一中心的回顾性审查.
- 收集的数据包括临床病理特征,手术细节 (拉巴光镜与开放式),以及患者的治疗结果.
主要成果:
- 八名男性患者 (平均年龄66.4岁) 接受了RCNU与阴道管. 四个手术是腹腔镜,四个是开放的.
- 高度UC和MIBC是常见的. 62.5%的人患有T3/4疾病,50%的人患有节点阳性. 两人有同步上路UC;其他人有脏受阻.
- 平均随访时间为31.6个月. 发生了四次复发和三次死于转移性疾病. 平均总生存时间为21.8个月;无病生存时间为19.3个月.
结论:
- 结合腹腔镜和开放RCNU是一种有效的治疗策略.
- 对于患有全神经瘤和MIBC的患者来说,RCNU是一个可行的选择,涉及非功能上泌尿道.
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