在患有脑的儿童中进行食控制,并与白质完整性相关联
Ophélie Martinie1,2, Philippe Karan3, Martin Simoneau1,4
1Center for Interdisciplinary Research in Rehabilitation and Social Integration (Cirris), CIUSSS de la Capitale-Nationale, Quebec City, QC, Canada.
Frontiers in neurology
|March 24, 2025
概括
患有脑 (CP) 的儿童在非主导手中表现出受损的前控制,这与白质通道完整性有关. 这表明更广泛的感觉运动问题有助于CP的运动缺陷.
科学领域:
- 神经科学是一个神经科学.
- 儿科 儿科 儿科
- 康复医学 康复医学 康复医学
背景情况:
- 大脑 (CP) 涉及影响运动控制的白质损伤.
- 关于CP的研究往往忽视了前控制及其与白质微观结构的联系.
- 了解这些缺陷对于CP儿童的日常活动表现至关重要.
研究的目的:
- 为了比较CP儿童与典型发育 (TD) 儿童的进食控制.
- 调查CP中前控制和白质微观结构之间的关系.
- 确定与CP的运动规划缺陷相关的特定白质道.
主要方法:
- 在9名CP儿童和40名TD儿童 (8-17岁) 中,比较了抓取和举起任务的性能.
- 利用扩散MRI来评估CP组中的白质微观结构.
- 分析了力控制,峰值力率和试验对试验的适应.
主要成果:
- 患有CP的儿童在非主导手中表现出前控制缺陷.
- 缺陷包括降低峰值力率和在试验中缺乏适应性.
- 在进食前对照组和皮质脊髓管/上纵的微观结构之间发现了强烈的相关性.
结论:
- 在患有CP的儿童的非主导手中,Feedforward控制受损.
- 皮层脊柱和上纵向囊的完整性与前控制有关.
- 更广泛的感觉运动过程可能有助于强制控制CP的缺陷.
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