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Updated: May 20, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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以目标为导向的设计和合成阿里尔功能化普罗米萨林类似物

Martina M Golden1, Carter U Brzezinski1, William M Wuest1,2

  • 1Department of Chemistry, Emory University, Atlanta, GA, 30322, USA.

Chembiochem : a European journal of chemical biology
|March 24, 2025
PubMed
概括

新的芳香类比的普罗米萨林被设计和合成,以对抗抗生素耐药性. 这些化合物对Pseudomonas aeruginosa表现出强烈的活性,为开发新型窄谱抗生素提供了有前途的战略.

关键词:
伪omonas aeruginosa 这种类型的病毒.抗菌剂是一种抗菌剂.不同的合成分歧.分子码头是分子码头.促沙林是一种促沙林.

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