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炎症性肠病特征和管理的时间趋势
Jessica C Young1, Lise M Helsingen2,3, Erle Refsum2,3
1Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Scandinavian journal of gastroenterology
|March 24, 2025
概括
最近的炎症性肠病 (IBD) 护理显示,内镜检查增加,免疫抑制剂和生物药物的使用增加. 结肠切除率有所下降,这表明IBD管理策略正在发展.
科学领域:
- 胃肠病学 胃肠病学
- 临床流行病学临床流行病学
背景情况:
- 炎症性肠病 (IBD) 的管理是复杂的.
- 对IBD进行内镜和药物治疗的进展已经存在,但它们对发病率和护理的影响尚不清楚.
研究的目的:
- 描述IBD管理的诊断和治疗实践的变化.
- 从1987年到2016年,分析IBD护理的趋势.
主要方法:
- 挪威和瑞典的全国登记处确定了1987年至2016年期间诊断的IBD患者.
- 详细的图表抽象在随机样本上进行.
- 实践被克罗恩病 (CD) 和性结肠炎 (UC) 分层,比较了生前 (1987-1999) 和生物 (2000-2016) 时期.
主要成果:
- 通过比较生物学和前生物学时期,内镜率增加,结肠镜变得更频繁,结肠切除率下降.
- 在生物期内,晚些时候 (2007年以后) 诊断的患者在一年内开始服用阿扎西奥普林,因弗利西马布和阿达利穆马布的比率更高.
结论:
- 最近的IBD护理显示出对更频繁的内镜检查的趋势.
- 在IBD管理中,免疫抑制剂和生物药物的使用越来越多.
- 在最近的时期,结肠切除率有所下降.
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