在有主观认知衰退的老年成年人中认知表现
Ramón López-Higes1, Susana Rubio-Valdehita2, David López-Sanz1,3
1Departamento de Psicología Experimental, Complutense University of Madrid (UCM), 28223 Madrid, Spain.
Geriatrics (Basel, Switzerland)
|March 24, 2025
概括
与认知健康个体相比,主观认知衰退 (SCD) 的老年人表现出在记忆和执行功能方面微妙但显著的差异. 这些认知变化,特别是抑制控制,可能有助于识别患有SCD的个体.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 认知心理学 认知心理学
背景情况:
- 主观认知衰退 (SCD) 在老年人群中越来越令人担忧.
- 早期识别认知变化对于及时干预至关重要.
- 了解SCD的神经心理特征对于将其与正常衰老区分开来至关重要.
研究的目的:
- 为了比较患有SCD的老年人与认知完整的对照者之间的认知功能.
- 为了确定与SCD相关的特定神经心理标志物.
- 开发一种临床工具来区分SCD与正常认知.
主要方法:
- 横截面研究比较33个个体的匹配组 (SCD与对照组).
- 广泛的神经心理评估,包括记忆,执行功能和语言.
- 包括后勤回归和ROC分析在内的统计分析.
主要成果:
- SCD组在延迟回忆,抑制控制和句子理解方面的得分明显较低.
- 在Stroop干扰任务上的表现较低与SCD的可能性更高有关.
- 在Stroop的干扰条件上,切断值得分为49,在分化小组中显示出临床效用.
结论:
- 与匹配的对照人群相比,患有SCD的老年人表现出微妙但显著的神经心理缺陷.
- 抑制性控制,特别是Stroop任务的性能,可以作为SCD的关键指标.
- 神经心理学评估可以帮助SCD的临床分化.
相关概念视频
Cognitive Development During Adulthood
36
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
36
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
86
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
86
Dementia
78
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
78
Cognitivism
1.3K
Cognitive psychology emerged as a significant field in the mid-20th century. It focused on understanding humans' internal mental processes. This approach emphasizes how people perceive, remember, think, and solve problems—elements critical to human cognition.
Previously dominated by behaviorism, which prioritized observable behaviors and largely ignored mental processes, psychology transformed in the 1950s. Cognitive psychologists argue that understanding how we think and process...
Previously dominated by behaviorism, which prioritized observable behaviors and largely ignored mental processes, psychology transformed in the 1950s. Cognitive psychologists argue that understanding how we think and process...
1.3K
Negative and Cognitive Symptoms of Schizophrenia
39
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
39
Working Memory
104
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
104


