报告抗生素使用与南卡罗来纳州医院Clostridioides difficile标准化感染比率之间的关联
Maya Abo-Hamzy1, Kayla Antosz2, Sarah E Battle3,4
1Medical University of South Carolina, Charleston, SC 29425, USA.
医院持续向国家医疗保健安全网络 (NHSN) 报告抗菌药物使用 (AU) 数据,显示*Clostridioides difficile*感染 (CDI) 标准化感染率 (SIR) 的减少更大. 这凸显了非洲联盟持续报告对抗微生物药物管理的重要性.
科学领域:
- 与医疗保健相关的感染
- 传染病流行病学 传染病流行病学
- 抗微生物药物管理管理
背景情况:
- 疾病控制和预防中心 (CDC) 建议医院向国家医疗保健安全网络 (NHSN) 报告抗菌素使用情况.
- 抗菌药物管理计划对于对抗*Clostridioides difficile*感染 (CDI) 等与医疗保健相关的感染至关重要.
研究的目的:
- 调查向NHSN报告的抗菌药物使用时间 (AU) 与*Clostridioides difficile*感染 (CDI) 标准化感染率 (SIR) 的变化之间的关联.
主要方法:
- 追溯性队列研究分析了2017年至2021年间来自南卡罗来纳州65家医院的数据.
- 医院的分类是基于报告AU≥3年而不是<3年.
- 用学生的t测试来比较两个组之间的CDI SIR平均变化.
主要成果:
- 报告AU长达3年以上的医院在CDI SIR下降幅度明显大于报告3年以上的医院 (平均差异为-0.33;p=0.016).
- 在医院中观察到CDI SIR的急剧下降,在研究期间,AU报告一致.
结论:
- 持续向NHSN报告抗微生物药物的使用与改善*Clostridioides difficile*感染的控制有关.
- 这些发现支持了CDC的建议,并强调了持续抗微生物药物管理努力的价值.
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