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Updated: May 20, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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SC-VAR:使用单细胞表观基因组数据解释多基因疾病风险的计算工具.

Gefei Zhao1,2, Binbin Lai1,2,3,4

  • 1Institute of Medical Technology, Peking University Health Science Center, 38 Xueyuan Rd, Hai Dian Qu, Beijing 100191, China.

Briefings in bioinformatics
|March 24, 2025
PubMed
概括

全基因组关联研究 (GWAS) 经常难以解释非编码变体. SC-VAR集成单细胞表观遗传学数据,以改善与疾病相关的基因和细胞类型的识别.

关键词:
疾病相关性得分得分 疾病相关性得分全基因组关联研究 (GWAS)没有编码的变体注释.多基因疾病的风险是多基因疾病的风险.单细胞表观基因组学

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