阿斯巴拉古斯酸,阿斯巴拉普丁和相关的滴醇衍生物与 ангиотензин转化酶-2 (ACE-2) 的相互作用:一个分子对接研究

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Updated: May 20, 2025

Nitropeptide Profiling and Identification Illustrated by Angiotensin II
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Nitropeptide Profiling and Identification Illustrated by Angiotensin II

Published on: June 16, 2019

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Gérard Vergoten1, Christian Bailly2,3

  • 1Univ. Lille, Inserm, U1286 - INFINITE - Lille Inflammation Research International Center, ICPAL, Lille, France.

Journal of biochemical and molecular toxicology
|March 24, 2025
PubMed
概括

研究了的化合物阿斯巴拉普丁与血管素转化酶2 (ACE2) 的结合. 阿斯巴拉丁B显示强大的结合,并确定了新的ACE2结合剂,如CMX-2043,这表明了新的药物设计可能性.

关键词:
血管酶转化酶 - 血管素转化酶阿斯巴拉古斯酸是一种酸.亚斯帕拉丁是一种阿斯巴拉丁.这就是dithiolane.药物与蛋白质结合的药物分子建模分子建模

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