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Updated: May 6, 2026

High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method
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大规模的组合选显示,抗生素耐药性格拉姆阴性ESKAPE病原体的小分子敏感化

Megan W Tse1,2, Meilin Zhu1,2, Benjamin Peters2

  • 1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.

Proceedings of the National Academy of Sciences of the United States of America
|March 24, 2025
PubMed
概括

一个新的高通量查平台发现了新型抗生素组合. 一种化合物,P2-56-3,通过破坏它们的外膜,强化了对抗性细菌的里法.

关键词:
这种细菌是Acinetobacter baumannii.抗生素组合 发现 发现抗生素增强剂 抗生素增强剂格拉姆阴性ESKAPE病原体的病原体协同效应是一种协同效应.

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