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中央TYK2抑制标识TYK2作为一个关键的神经免疫调节器

Tyler P Molitor1, Genki Hayashi1, Mei-Yao Lin1

  • 1Department of Biology, Neuron23, Inc., South San Francisco, CA 94080.

Proceedings of the National Academy of Sciences of the United States of America
|March 24, 2025
PubMed
概括

中枢神经系统 (CNS) 氨酸激酶2 (TYK2) 抑制减少神经炎症,为多发性硬化症 (MS) 提供潜在的治疗策略. 穿透大脑的TYK2抑制剂在临床前模型中显示出显著的保护作用.

关键词:
欧洲电子商务管理局 (EEAE)这就是TYK2TYK2.这是自身免疫力.状细胞是状细胞中的一种.神经炎症是一种神经炎症.

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