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不同的甘油三糖指数相关指标与过度活跃的膀之间的关联
Yuhan Huang1, Kaiyuan Wang1, Wenjing Wang1
1Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Jilin, Changchun, China.
Diabetes research and clinical practice
|March 24, 2025
概括
代谢异常与过度活跃的膀 (OAB) 有关. 这项研究发现,甘油三糖 (TyG) 指数指标与OAB相关,TyG-WHtR显示出最强的预测能力.
科学领域:
- 代谢健康和泌尿病学
- 生物统计学和流行病学
背景情况:
- 过度活跃的膀 (OAB) 的特征是尿急.
- 代谢异常与OAB的发病有关.
- 调查甘油三糖 (TyG) 指数指标与OAB的关联是至关重要的.
研究的目的:
- 检查各种TyG指数相关指标与OAB之间的关系.
- 评估这些指标对OAB的预测能力.
主要方法:
- 来自NHANES 2005-2018的9024名参与者 (年龄≥20岁) 的分析.
- 进行了加权的多变量逻辑回归,子组和相互作用分析.
- 通过ROC分析,DeLong的测试和混矩阵评估了预测性能.
主要成果:
- TyG指数指标显示了与OAB的积极关联.
- 关联在不同年龄和体育活动子组之间有显著的差异 (p对相互作用<0.1).
- 在整体人群中,TyG-WHtR表现出最高的预测能力 (AUC = 0.625),特别是在60岁以下的个人和中度至强度体力活动的人群中.
结论:
- 在TyG指数指标和OAB之间存在积极的关联.
- 在一般人群中,TyG-WHtR显示了OAB最强的预测性能.
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