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Updated: May 20, 2025

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固相合成和细胞毒性评价的新型金二化物

Sadaiyan Govindaraj1, Kilivelu Ganesan2, Perumal Elumalai3

  • 1Department of Chemistry, Presidency College, Chennai, 600005, India.

Scientific reports
|March 25, 2025
PubMed
概括

使用微波辅助方法高效合成了基于胺基的新型金化化合物,显示反应时间缩短和产量高. 这些化合物被评估为肺癌细胞毒性和潜在的B-Raf激酶抑制.

关键词:
基于胺基的金.原子经济 原子经济煮蛋的情节图片细胞毒性 细胞毒性分子对接是分子对接.没有溶剂的反应.

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Arenediazonium substitution reactions occur when the diazonium group is substituted by various functional groups such as halides, hydroxyl, nitrile, etc. For instance, arenediazonium salts react with copper(I) salts of chloride, bromide, or cyanide to form corresponding aryl chlorides, bromides, and nitriles. These reactions are named Sandmeyer reactions. Although the mechanism of this reaction is complicated, as illustrated in Figure 1, they are believed to progress via an aryl copper...
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