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Updated: May 20, 2025

Imaging and Quantifying Mitochondrial Morphology in C. elegans During Aging
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改善TIMM50损失通过改善线粒体结构和功能来减缓衰老

Amrita Nepalia1, Deepak Kumar Saini1,2,3

  • 1Department of Developmental Biology and Genetics, Indian Institute of Science, Bengaluru, 560012, India.

Advanced biology
|March 25, 2025
PubMed
概括

线粒体功能障碍是衰老的标志,与内线粒体膜50 (TIMM50) 的转位酶减少有关. 较低的TIMM50水平会触发衰老,而其过度表达会减缓衰老. 这一发现提供了新的抗衰老策略.

关键词:
TIMM50 TIMM50 的时间.衰老的衰老 衰老的衰老细胞衰老 细胞衰老线粒体中的线粒体.这里是Sirtuin.

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