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Updated: May 20, 2025

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在小鼠模型和灵长类动物安全研究中对pritumumab的表征

Avani A Mody1, Rajesh Mukthavaram2,3, Pengfei Jiang2

  • 1CureScience Institute, San Diego, CA, USA.

Scientific reports
|March 25, 2025
PubMed
概括

普利图马布有效向并抑制质母细胞瘤和胰腺癌的生长. 临床前研究表明,它穿过血脑屏障,在灵长类动物中是安全的,支持正在进行的大脑癌症临床试验.

关键词:
动物模型动物模型血液大脑屏障 血液大脑屏障免疫治疗是一种免疫疗法.普里图穆马布 (Pritumumab) 是一种可怕的药物.在Vimentin中,使用了Vimentin.

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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