心力衰竭,痴呆症与中风严重程度的增加,住院死亡率和并发症有关
Lijun Zuo1, YanHong Dong2, Yang Hu1
1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
ESC heart failure
|March 25, 2025
概括
患有心力衰竭 (HF) 和痴呆症的中风患者在医院死亡率和并发症显著增加. 共同管理这些疾病对于改善中风患者的治疗结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 老年病的医生 老年病的医生
背景情况:
- 心力衰竭 (HF) 是已知的缺血性中风的危险因素.
- 包括痴呆症在内的认知障碍在HF和中风患者中普遍存在.
- 关于并发性HF和痴呆症中风患者的特征和结果的研究有限.
研究的目的:
- 研究心力衰竭 (HF) 和痴呆症同时存在的中风患者的临床特征,住院死亡率和并发症.
- 为了比较四组的结果:脑卒中与痴呆症/没有HF,脑卒中与HF/没有痴呆症,脑卒中与HF和痴呆症,脑卒中没有任何条件.
主要方法:
- 利用来自中国中风中心联盟数据库的数据.
- 根据HF和痴呆症的存在将患者分为四组.
- 分析了住院死亡率和并发症 (肺炎,,肺栓塞,心肌梗塞,胃肠道出血,深静脉血栓).
- 采用多变量逻辑回归来评估HF,痴呆,中风和功能结果之间的关联.
主要成果:
- 患有痴呆症和高血压的中风患者年龄较大,患有更多的并发症,如周围血管疾病和脂质失调症.
- 与对照组相比,所有三组患有HF或痴呆症或两者都表现出较高的住院死亡率和并发症率.
- 与没有HF或痴呆症的患者相比,患有HF和痴呆症的患者在医院死亡率显著增加 (调整后OR,2.875) 和肺炎,,肺栓塞的风险更高.
结论:
- 患有痴呆症和心力衰竭并存的中风患者患有住院死亡率和并发症的风险增加.
- 强调需要加强痴呆症和HF患者的风险因素控制,以预防中风和改善结果.
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