pituitary apoplexy 的临床特征和管理中的与年龄相关的差异:一个队列研究
Esteban Cordero Asanza1, Antonio Biroli1, Carlos Pérez-López2
1Neurosurgery Department, Hospital Universitario Vall de Hebrón, Departament de Cirurgia i Ciències Morfològiques, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.
European journal of endocrinology
|March 25, 2025
概括
在年轻和年长的成年人中,脑下垂体中风 (PA) 的管理和结果是相似的. 像MRI这样的高级成像对于诊断PA至关重要,特别是在老年患者中.
科学领域:
- 内分泌学 在内分泌学.
- 神经学 神经学
- 神经外科 神经外科
背景情况:
- 垂体中风 (PA) 是一种罕见的,急性疾病,涉及垂体腺出血或心脏病发作.
- 了解PA的年龄相关差异对于优化患者护理至关重要.
研究的目的:
- 为了比较PA的临床特征,治疗方法和结果,在65岁以下和65岁以上的患者中.
- 为了确定潜在的年龄特异因素影响PA呈现和治疗.
主要方法:
- 在西班牙18家医院对301名PA患者 (2010-2023) 进行了回顾性多中心研究.
- 对人口统计,临床表现,治疗和结果的分析,按年龄分层 (<65岁与≥65岁).
主要成果:
- 老年患者 (≥65岁) 呈现出更多的并发症,但类似的临床/放射学发现,除了更高的神经麻频率.
- 在不同年龄组中,手术和保守治疗率是可比的.
- 组织病理学显示老年患者的亡增加;包括死亡率在内的结果在各年龄组中相似.
结论:
- 在年轻和老年患者中,尽管老年人患上并发症增加,但PA的管理和结果是可比的.
- 瘤生物学中可能存在与年龄相关的差异,需要进一步调查.
- 磁共振成像 (MRI) 建议用于PA诊断,特别是在老年患者中,以检测缺血性死性PA.
关键词:
脑震荡症 (apoplexy) 是一种脑震荡症.保守的管理方式.年长的老人老年人老年人.年龄较大的个人年龄较大的个人pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary 下垂体 下垂体 下垂体 下垂体 下垂体 下垂体 下垂体 下垂体手术 手术 手术 手术 手术 手术 手术更多相关视频
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