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Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
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作为多目标治疗剂的硫胺载体皮拉佐衍生物:设计,合成,表征,生物评估,在中ADME/T剖析和分子对接研究

Nebih Lolak1, Suleyman Akocak1, Meryem Topal2

  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Adıyaman University, Adıyaman, Turkey.

Pharmacology research & perspectives
|March 25, 2025
PubMed
概括

新型含硫胺的pyrazolone衍生物被合成并测试为胆酶 (ChEs) 和碳酸无水酶 (CA) 的抑制剂. 这些化合物显示出通过选择性抑制这些酶来治疗阿尔茨海默病和青光眼的潜力.

关键词:
碳酸酶抑制剂 碳酸酶抑制剂胆酶抑制剂 胆酶抑制剂玻璃眼 glaucoma 玻璃眼 玻璃眼 玻璃眼 玻璃眼分子对接的分子对接.含有硫胺的pyrazolones是什么意思

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