在6个月的肺结核治疗期间,持续数字咳监测
Mihaja Raberahona1,2,3, Alexandra Zimmer4,5,3, Rivonirina Andry Rakotoarivelo2,6,7
1Department of Infectious Diseases, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar.
ERJ open research
|March 25, 2025
概括
使用人工智能驱动的智能手机应用程序的持续咳监测 (CCM) 可以跟踪肺结核 (PTB) 治疗. 在PTB治疗期间,咳显著减少,显示CCM.
科学领域:
- 数字健康数字健康
- 人工智能的人工智能
- 肺部医学 肺部医学
背景情况:
- 数字和可穿戴技术与人工智能使持续咳监测 (CCM) 能够对肺结核 (PTB) 的客观症状评估.
- CCM作为一种替代标记,用于评估PTB患者的治疗疗效.
研究的目的:
- 描述成年人PTB治疗期间咳症状的演变.
- 评估实施基于社区的CCM的可行性.
主要方法:
- 在治疗开始时,成人PTB参与者的潜在招募.
- 使用带有AI算法检测咳的智能手机应用程序进行持续6个月的咳监测.
主要成果:
- 从第1周 (11.0) 到第8周 (3.5) (p=0.002) 观察到每小时中位咳 (medCPH) 的显著减少.
- 在26周 (治疗结束) 时,medCPH进一步下降到1.0.
- 在最初的13周内,人们注意到对CCM的高度坚持,随后下降;坚持在白天和晚上之间是一致的.
结论:
- 在PTB治疗的密集阶段,咳数量迅速下降,并在治疗结束时逐渐达到低基线.
- 使用数字技术的基于社区的CCM在资源较少的环境中是可行的.
- 需要进一步评估替代方法,以应对遵守挑战和技术限制,如移动互联网和电力接入.
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