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Updated: May 20, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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通过结合电子提取功能,抗囊体N-基胺的结构活性关系

Ameera Mohammed Dawoodjee1, John Sichinga1, Harrison Banda1

  • 1Department of Chemistry, School of Natural Sciences, University of Zambia, P.O. Box 32379, Lusaka, Zambia.

Results in chemistry
|March 25, 2025
PubMed
概括

研究人员探索了新的N-phenylbenzamide类似物,以对抗Schistosoma mansoni平虫. 虽然效力下降,但38化合物表现有前途,具有广泛的选择性指数,表明毒性降低.

关键词:
作为N-phenylbenzamide的类似物,它具有类似的作用.这是一种N-pyridazinylbenzamide类似物.这种病原体是Schistosoma mansoni.

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