退伍军人中的SARS-CoV-2感染,疫苗接种和刺激性肠综合征:一个跨部门研究
Arash Oliver Parsi1, George Nicholas Verne2,3, Yu Jiang4
1Metairie Park Country Day School, Metairie, USA.
感染COVID-19显著增加了患上易怒肠综合征 (IBS) 的风险. 接种COVID-19疫苗可以降低这种风险,可以保护感染和随后的IBS发展.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 需要进一步调查SARS-CoV-2 (COVID-19) 感染和易怒肠综合征 (IBS) 之间的关系.
- 了解这种关联对于管理感染后的后果至关重要.
研究的目的:
- 确定COVID-19感染和IBS之间的潜在机械联系.
- 评估COVID-19疫苗接种在这种关系中的作用.
主要方法:
- 一项横截面研究分析了来自退伍军人事务电子医疗保健数据库的9112名退伍军人.
- 数据包括人口统计,COVID-19感染史,疫苗接种状态和IBS诊断.
- 采用了单变量和多变量逻辑回归模型.
主要成果:
- COVID-19 感染与IBS (OR=1.94) 的几率增加显著相关.
- 接种COVID-19疫苗显著与IBS的几率降低相关 (OR=1.49).
- 没有COVID-19感染的接种疫苗的人比患有COVID-19的未接种疫苗的人有较低的IBS风险.
结论:
- 感染COVID-19几乎使得患上IBS的可能性增加了一倍.
- 通过减少感染可能性,COVID-19疫苗接种减轻了IBS风险.
- 疫苗接种策略可以减少退伍军人群中IBS发展的整体风险.
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